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Clinical Studies

There have been numerous double-blind scientific studies proving a significant reduction (at least 50%) in migraine severity, migraine attack frequency, and duration of migraine headaches in migraine sufferers who take magnesium, riboflavin, coenzyme Q10, and butterbur supplements.

Alternative headache treatments: nutraceuticals, behavioral and physical treatments- PubMed- NCBI
Butterbur: an alternative therapy for migraine prevention- PubMed- NCBI
Role of magnesium in the pathogenesis and treatment of migraine- PubMed-NCBI
Role of Magnesium, Coenzyme Q10, Riboflavin, and Vitamin B12 in Migraine Prophylaxis
[Effectiveness of chemical, herbal and dietetic migraine prophylactics. An overview of randomized controlled double-blind studies]- PubMed- NCBI
Pathophysiological basis of migraine prophylaxis
Non-pharmacological management of migraine during pregnancy- PubMed- NCBI
Effectiveness of high-dose riboflavin in migraine prophylaxis. A randomized controlled trial- PubMed- NCBI
Non-pharmacological approach to migraine prophylaxis: part II- PubMed- NCBI
Relation between serum magnesium level and migraine attacks- PubMed- NCBI
Coenzyme Q10 deficiency and response to supplementation in pediatric and adolescent migraine- PubMed- NCBI
Herbal Extract Reduces Migraines
Cephalalgia. 1996 Jun;16(4):257-63
Headache. 2005 Mar;45(3): 196-203.
Eur Neurol. 2004;51(2):89-97. Epub 2004 Jan 28.
Neurology. 2004 Dec 28; 63(12):2240-4.

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