Posts Tagged ‘causes migraines’

Risk Factors for Migraines

Wednesday, March 3rd, 2010

The primary risk factor of migraines is genetics. Researchers have found that 70% to 80% of people with this condition have a family history of migraines.

Migraines affect more women than men. Nearly 75% of people afflicted are women. There seems to be some correlation between female hormones and migraines. Examples of such hormones are estrogen and progesterone. Throughout a woman’s cycle, levels of these hormones increase and decrease, and cause migraines in those who are migraine-prone.

About 5 – 10% of children suffer from migraines. In contrast to adults, boys and girls suffer equally, but are less likely to have migraines when they reach adulthood. Some girls experience migraines more frequently after puberty, but puberty is not the cause of migraines.

The majority of people suffering from migraines are between 15 and 55 years of age.

There are medical conditions that have a tendency to be present in people with migraines. These include depression, epilepsy, anxiety, high blood presser and stroke. They do not cause migraines nor do they increase the likelihood of a person developing a migraine. Yet, these problems may accompany migraines.

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Biological Migraine Origins

Tuesday, February 9th, 2010

An article in Scientific American (August 2008) attempts to explain the causes of migraines.

People who are prone to migraines may think that they are caused by stress, menstruation, sleep deprivation, exercise, etc. But, these same triggers don’t cause migraines in the majority of the population.

It was believed that a decrease in blood flow causes a migraine. New research, however, shows that immediately prior to the onset of a migraine, blood flow is increased by 300 percent.  When the migraine occurs, surprisingly, there is a normal blood flow.  Does this increased blood flow cause the migraine?

Studies of the aura condition which presents itself prior to the onset of migraines has given scientists a better understanding of migraines. Cortical spreading depression creates this aura. Cortical spreading depression is a minefield of nerve cell activity that occurs in the outer layer of the cortex, in the area of the brain that controls vision.   (This would explain the aura.) This is followed by a resting phase of the neurons.

Area of cortex that controls vision:

It is possible that the increase in blood flow prior to a migraine is necessary to provide the neurons with the energy they need to fire off signals.

Nerve cell activity is maintained by the flow of sodium, potassium and calcium ions across the nerve cell membrane. The gatekeepers of these ions are pumps. Basically, the pumps make sure that a nerve cell at rest has a large amount potassium, but low amounts of sodium and calcium.

In a migraine sufferer, the pumps and channels are defective. Scientists have isolated three genetic mutations that are each capable of being responsible for causing migraines.

Even so, genetics alone do not account for migraines. There are studies of identical twins where one twin will suffer from migraines and the other will not.

We are the manufacturers of Migravent, a dietary supplement that contains magnesium. According to PubMed, studies have shown the effectiveness of magnesium in calming the hyperactive nerve cells of migraine sufferers.

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